Mogutov S S, Sergeyeva E S, Evgraf'ev V P
Kosm Biol Aviakosm Med. 1984 May-Jun;18(3):61-5.
The rearrangement of the adrenal-hypothalamus-pituitary system of rats kept in a low-temperature hypoxic-hypercapnic atmosphere was investigated. Phasic changes of the system were detected, with their magnitude and sign depending on the exposure time. The central and peripheral components of the system developed specific relations. One of the peculiarities of the responses of the adrenal-hypophysis-pituitary system to the above exposure is a limited range of changes in the neuroendocrine activities due to a total reactivity decrease. This protects the neuroendocrine system from overstrain or involvement in overshooting reactions. It is assumed that this type of response of the adrenal-hypophysis-pituitary system is important to help understand mechanisms of the neuroendocrine regulation of the adaptive process developing in response to the combined effect.
研究了置于低温低氧高碳酸血症环境中的大鼠肾上腺-下丘脑-垂体系统的重排情况。检测到该系统的阶段性变化，其幅度和特征取决于暴露时间。该系统的中枢和外周成分形成了特定的关系。肾上腺-垂体-下丘脑系统对上述暴露的反应特点之一是，由于总反应性降低，神经内分泌活动的变化范围有限。这保护了神经内分泌系统免于过度紧张或参与过度反应。据推测，肾上腺-垂体-下丘脑系统的这种反应类型对于理解在联合作用下发生的适应性过程的神经内分泌调节机制很重要。
