Rodgers B M, Dix P M, Talbert J L, McGuigan J E
J Pediatr Surg. 1978 Feb;13(1):13-6. doi: 10.1016/s0022-3468(78)80204-8.
Serum gastrin determinations were performed in 32 normal-term infants to determine the level of this hormone in normal infants at birth and its response to normal feeding. Significant differences were noted between newborn cord blood and maternal blood at birth. Further significant elevations in fasting serum gastrins were noted in these infants over the first 72 hr of life. Pre- and postprandial determinations with normal feeding failed to demonstrate a significant elevation in serum gastrin levels following ingestion of protein-containing formulas. These data suggest a relative insensitivity of the release of gastrin from the gastric antrum in response to protein, a powerful mediator of gastrin release in the adult.
对32名足月正常婴儿进行血清胃泌素测定，以确定正常婴儿出生时该激素的水平及其对正常喂养的反应。出生时新生儿脐带血与母体血之间存在显著差异。在这些婴儿出生后的头72小时内，空腹血清胃泌素进一步显著升高。正常喂养前后的测定未能显示摄入含蛋白质配方奶后血清胃泌素水平有显著升高。这些数据表明，胃窦释放胃泌素对蛋白质相对不敏感，而蛋白质是成年人胃泌素释放的有力介质。
