婴儿肥厚性幽门狭窄时的血清胃泌素水平。对胃泌素分泌试验的反应。
Serum gastrin levels in hypertrophic pyloric stenosis of infancy. Response to a gastrin secretion test.
作者信息
Hambourg M A, Mignon M, Ricour C, Accary J, Pellerin D
出版信息
Arch Dis Child. 1979 Mar;54(3):208-12. doi: 10.1136/adc.54.3.208.
The aim of this study was to look for a difference in fasting serum gastrin levels or in serum gastrin response to oral feeding between infants with hypertrophic pyloric stenosis and normal controls. Fasting serum gastrin levels were measured by radioimmunoassay in 10 patients with pyloric stenosis, before pyloromyotomy and 7 and 15 days after it, and in 11 controls. In addition, the serum gastrin responses to a casein hydrolysate meal were studied in both groups (in the patients, 7 days after operation). The fasting serum gastrin levels in the patients did not differ from those in the controls before operation, but they did so after it. The serum gastrin response to feeding in patients after pyloromyotomy was no greater than in controls.
本研究的目的是探寻肥厚性幽门狭窄婴儿与正常对照组之间空腹血清胃泌素水平或口服喂养后血清胃泌素反应的差异。采用放射免疫分析法对10例幽门狭窄患者在幽门肌切开术前、术后7天和15天以及11例对照组进行空腹血清胃泌素水平测定。此外，两组均研究了对酪蛋白水解物餐的血清胃泌素反应（患者在术后7天）。患者术前空腹血清胃泌素水平与对照组无差异，但术后有差异。幽门肌切开术后患者进食后的血清胃泌素反应并不高于对照组。
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