Urinary anthracycline metabolites from mice treated with adriamycin and N-trifluoroacetyladriamycin-14-valerate.

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作者信息

Israel M, Pegg W J, Wilkinson P M

出版信息

J Pharmacol Exp Ther. 1978 Mar;204(3):696-701.

PMID:633073

Abstract

摘要

相似文献

Urinary anthracycline metabolites from mice treated with adriamycin and N-trifluoroacetyladriamycin-14-valerate.

J Pharmacol Exp Ther. 1978 Mar;204(3):696-701.

N-trifluoroacetyladriamycin-14-valerate, an analog with greater experimental antitumor activity and less toxicity than adriamycin.N-三氟乙酰阿霉素-14-戊酸酯，一种比阿霉素具有更强实验性抗肿瘤活性且毒性更小的类似物。

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A differential interaction of daunomycin, adriamycin, and N-trifluoroacetyladriamycin 14-valerate with mouse peritoneal macrophages.

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Protein-associated DNA breaks and DNA-protein cross-links caused by DNA nonbinding derivatives of adriamycin in L1210 cells.阿霉素的DNA非结合衍生物在L1210细胞中引起的蛋白质相关DNA断裂和DNA-蛋白质交联。

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Differences in cellular uptake and cytofluorescence of adriamycin and N-trifluoroacetyladriamycin-14-valerate.

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Synthesis and antitumor activity of 4-demethoxyadriamycin and 4-demethoxy-4' -epiadriamycin.4-去甲氧基阿霉素和4-去甲氧基-4'-表阿霉素的合成及其抗肿瘤活性

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Comparative effects of adriamycin and N-trifluoroacetyladriamycin-14-valerate on cell kinetics, chromosomal damage, and macromolecular synthesis in vitro.

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Pharmacologic studies with radiolabeled N-trifluoroacetyladriamycin-14-valerate (AD 32). Comparison of total anthracycline fluorescence and radioactivity in mouse serum and urine.

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Effect of adriamycin and analogs on the nuclear fluorescence of propidium iodide-stained cells.

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Effects of N-trifluoroacetyladriamycin-14-valerate and related agents on DNA strand damage and thymidine incorporation in CCRF-CEM cells.N-三氟乙酰阿霉素-14-戊酸酯及相关药物对CCRF-CEM细胞DNA链损伤和胸腺嘧啶核苷掺入的影响。

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引用本文的文献

Pharmacologic studies with radiolabeled N-trifluoroacetyladriamycin-14-valerate (AD 32). Comparison of total anthracycline fluorescence and radioactivity in mouse serum and urine.

Cancer Chemother Pharmacol. 1980;4(2):79-82. doi: 10.1007/BF00254026.

Distribution of radioactivity and anthracycline-fluorescence in tissues of mice one hour after [14C]-labeled AD 32 administration. Evidence for tissue aglycone formation.

Cancer Chemother Pharmacol. 1981;6(1):25-30. doi: 10.1007/BF00253006.

Radioactive species in rat urines and tissues after [14C] AD 32 administration.

Cancer Chemother Pharmacol. 1984;12(3):154-6. doi: 10.1007/BF00256537.

Comparative effects of adriamycin and DNA-non-binding analogues on DNA, RNA, and protein synthesis in vitro.阿霉素与非DNA结合类似物对体外DNA、RNA及蛋白质合成的比较作用

Cancer Chemother Pharmacol. 1987;20(4):277-84. doi: 10.1007/BF00262577.

Comparative metabolism and excretion of adriamycin in man, monkey, and rat.阿霉素在人、猴和大鼠体内的代谢及排泄比较

Cancer Chemother Pharmacol. 1979;2(2):121-5. doi: 10.1007/BF00254084.

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