Minar E, Ehringer H, Sommer G, Marosi L, Czembirek H
AJR Am J Roentgenol. 1984 Sep;143(3):629-32. doi: 10.2214/ajr.143.3.629.
The incidence of postphlebographic venous thrombosis was investigated by 125I-labeled fibrinogen uptake tests in 60 patients whose veins were flushed with saline solution containing 10,000 IU of heparin after leg phlebography. Ionic methylglucamine iodamide was used as the contrast medium. In six patients superficial thrombophlebitis extending from the contrast-medium injection site was observed after phlebography. The incidence of deep venous thrombosis was 3.3%, significantly less than that reported for studies using triiodinated ionic contrast media without flushing the veins with a heparin solution. It is comparable to the incidence of venous thrombosis reported after using nonionic contrast media. The authors conclude that flushing the veins with heparinized saline solution can improve the safety of phlebography considerably.
通过125I标记的纤维蛋白原摄取试验，对60例在腿部静脉造影后用含10000 IU肝素的盐溶液冲洗静脉的患者进行了静脉造影后静脉血栓形成的发生率调查。离子型甲葡胺碘酰胺用作造影剂。在6例患者中，静脉造影后观察到从造影剂注射部位延伸的浅表血栓性静脉炎。深静脉血栓形成的发生率为3.3%，明显低于使用三碘离子型造影剂且未用肝素溶液冲洗静脉的研究报告的发生率。这与使用非离子型造影剂后报告的静脉血栓形成发生率相当。作者得出结论，用肝素化盐溶液冲洗静脉可显著提高静脉造影的安全性。
