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流感嗜血杆菌作为男性尿路感染的病因

Hemophilus influenzae as a cause of urinary tract infections in men.

作者信息

Gabre-Kidan T, Lipsky B A, Plorde J J

出版信息

Arch Intern Med. 1984 Aug;144(8):1623-7.

PMID:6331807
Abstract

Hemophilus influenzae has rarely been reported to cause urinary tract infections, but media supportive of its growth are not routinely used for urine cultures. At two Veterans Administration medical centers, H influenzae was isolated from the urine of eight men in the past four years. All had anatomic or functional genitourinary abnormalities, and half had had chronic pyelonephritis or recurrent urinary tract infections. Three patients had acute cystitis, two patients had pyelonephritis, two patients had prostatitis, and one patient had asymptomatic bacteriuria with pyuria. Cases were discovered by primary isolation on chocolate agar or sheep's blood agar, by "satelliting" around staphylococci, or by positive urine Gram's stains. Urine Gram's stains disclosed organisms in all six nonprostatitis cases. Organisms were all nonserotypable, were of biotypes 2, 3, or 4, and were beta-lactamase negative. Hemophilus influenzae may be a more common uropathogen in adults than previously recognized.

摘要

流感嗜血杆菌极少被报道可引起尿路感染,但支持其生长的培养基并非常规用于尿培养。在两家退伍军人管理局医疗中心,过去四年里从八名男性的尿液中分离出了流感嗜血杆菌。所有患者均有解剖学或功能性泌尿生殖系统异常,半数患者曾患慢性肾盂肾炎或复发性尿路感染。三名患者患有急性膀胱炎,两名患者患有肾盂肾炎,两名患者患有前列腺炎,一名患者有无症状菌尿伴脓尿。病例是通过在巧克力琼脂或羊血琼脂上进行初次分离、在葡萄球菌周围“卫星生长”或尿革兰氏染色阳性发现的。尿革兰氏染色在所有六例非前列腺炎病例中均发现了细菌。分离出的细菌均不可分型,属于生物型2、3或4,且β-内酰胺酶阴性。流感嗜血杆菌在成年人中可能是一种比以往认识到的更为常见的尿路病原体。

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