Arffa R C, Schlaegel T F
Arch Ophthalmol. 1984 Aug;102(8):1153-5. doi: 10.1001/archopht.1984.01040030931016.
To determine the incidence of chorioretinal lesions in patients with Fuchs' heterochromic iridocyclitis, we reviewed the records of all patients with this disease seen at the Indiana University Uveitis Service, Indianapolis, since 1963. For comparison the records of age- and sex-matched patients with HLA-B27-positive iritis were also reviewed. The incidence of chorioretinal lesions in one or both eyes of patients with Fuchs' heterochromic iridocyclitis was significantly higher than in the patients with HLA-B27-positive iritis or than expected in the general population. Among the types of lesions manifested, the most notable increase was in toxoplasmosislike lesions. However, two of the five patients with these lesions had negative indirect hemagglutination assays for toxoplasmosis, down to undiluted serum. The reason for the high incidence of chorioretinal lesions in patients with Fuchs' heterochromic iridocyclitis is unclear and may be related to immunologic changes in these patients.
为了确定富克斯异色性虹膜睫状体炎患者脉络膜视网膜病变的发病率，我们回顾了自1963年以来在印第安纳波利斯市印第安纳大学葡萄膜炎服务中心就诊的所有该病患者的记录。作为对照，我们也回顾了年龄和性别匹配的HLA - B27阳性虹膜炎患者的记录。富克斯异色性虹膜睫状体炎患者单眼或双眼出现脉络膜视网膜病变的发病率显著高于HLA - B27阳性虹膜炎患者，也高于一般人群的预期发病率。在所表现出的病变类型中，最显著增加的是弓形虫样病变。然而，五名患有这些病变的患者中有两名弓形虫间接血凝试验结果为阴性，血清原液检测也是如此。富克斯异色性虹膜睫状体炎患者脉络膜视网膜病变发病率高的原因尚不清楚，可能与这些患者的免疫变化有关。
