Schwab I R
Department of Ophthalmology, West Virginia University, Morgantown.
Am J Ophthalmol. 1991 Mar 15;111(3):356-62. doi: 10.1016/s0002-9394(14)72322-0.
Between January 1983 and July 1987, I examined 25 patients at the Department of Ophthalmology, West Virginia University, who had the anterior segment characteristics of Fuchs' heterochromic iridocyclitis. Of these patients, 16 had fundus lesions suggestive of ocular toxoplasmosis. Of these 16 patients, 13 had a positive serologic test for toxoplasmosis, two patients were not tested, and one patient had a negative test at 1:16. The remaining nine patients with Fuchs' heterochromic iridocyclitis had no fundus lesions suggestive of toxoplasmosis. A chart review of 792 consecutive patients at the Retinal Unit, West Virginia University, during a six-month period disclosed that 24 of 590 patients (4%) had chorioretinal scars suggestive of toxoplasmosis. I concluded from these data that in at least one subgroup of patients with Fuchs' heterochromic iridocyclitis there is a significant association with the chorioretinal scars of toxoplasmosis (P less than .01), and this is suggestive of a causal relationship.
1983年1月至1987年7月期间，我在西弗吉尼亚大学眼科检查了25例具有富克斯异色性虹膜睫状体炎眼前节特征的患者。在这些患者中，16例有提示眼弓形虫病的眼底病变。在这16例患者中，13例弓形虫病血清学检测呈阳性，2例未检测，1例1:16检测结果为阴性。其余9例富克斯异色性虹膜睫状体炎患者没有提示弓形虫病的眼底病变。对西弗吉尼亚大学视网膜科连续792例患者进行的为期6个月的病历回顾显示，590例患者中有24例（4%）有提示弓形虫病的脉络膜视网膜瘢痕。我从这些数据中得出结论，在至少一个富克斯异色性虹膜睫状体炎患者亚组中，与弓形虫病的脉络膜视网膜瘢痕存在显著关联（P小于0.01），这提示存在因果关系。
