Neu H C
Semin Urol. 1983 May;1(2):130-7.
A better understanding of the pathophysiology of urinary infection has markedly altered treatment programs. Single-dose therapy should be used for infections limited to the bladder. In contrast, treatment periods of 4-6 wk are needed to yield the best cure rates in upper tract infections. TMP/SMX thrice weekly has proved to be a successful prophylactic program for women with recurrent urinary infection. In contrast to the female, young children and men require longer therapy periods for urinary infection and should always have a detailed radiologic and urologic evaluation to eliminate the possibility of structural abnormalities.
对尿路感染病理生理学的更好理解显著改变了治疗方案。单剂量疗法应用于局限于膀胱的感染。相比之下，上尿路感染需要4至6周的治疗期才能获得最佳治愈率。对于复发性尿路感染的女性，每周三次服用复方新诺明已被证明是一种成功的预防方案。与女性不同，幼儿和男性尿路感染需要更长的治疗期，并且应始终进行详细的放射学和泌尿科评估，以排除结构异常的可能性。
