Redmond S R, Pichichero M E
JAMA. 1984 Nov 9;252(18):2581-4. doi: 10.1001/jama.252.18.2581.
Day-care centers are a relatively new phenomena of American society that bring together large numbers of young children susceptible to contagious disease. This study examines the incidence and risk factors of endemic Hemophilus influenzae type b disease both in the general population and in day-care attendees in Monroe County, New York, for 1982 and 1983. The attack rate in the general population (excluding day-care attendees) was highest in children younger than 1 year (131.9 cases per 100,000 per year) and in those 1 to 2 years old (75.7 cases per 100,000 per year) compared with older children. The relative risk for day-care attendees was much greater than that of the general population. It was 12.3 times greater for children younger than 1 year, 7.2 times greater for those 1 to 2 years old, and 3.8 times greater for those 2 to 3 years old. We conclude that children attending day-care facilities face a substantial increased risk of contracting invasive H influenzae type b disease. Efforts to prevent susceptibility and contagious spread of this disease in this population seem necessary.
日托中心是美国社会中一种相对较新的现象，它将大量易感染传染病的幼儿聚集在一起。本研究调查了1982年和1983年纽约门罗县普通人群以及日托中心儿童中b型流感嗜血杆菌地方性疾病的发病率和危险因素。普通人群（不包括日托中心儿童）的发病率在1岁以下儿童中最高（每年每10万人中有131.9例），1至2岁儿童中次之（每年每10万人中有75.7例），高于年龄较大的儿童。日托中心儿童的相对风险远高于普通人群。1岁以下儿童的相对风险高12.3倍，1至2岁儿童高7.2倍，2至3岁儿童高3.8倍。我们得出结论，日托中心的儿童感染侵袭性b型流感嗜血杆菌疾病的风险大幅增加。在这一人群中预防该疾病的易感性和传染性传播的努力似乎是必要的。
