Higa T, Tanada S, Taki W, Fukuyama H, Fujita T, Horiuchi K S, Minato K, Hamanaka D, Odori T, Yonekawa Y
Radiat Med. 1983 Apr-Jun;1(2):137-45.
A tomographic study of regional cerebral blood flow and hemodynamics was performed on 25 patients with cerebrovascular diseases by selective continuous infusion of krypton-81m (Kr-81m). Kr-81m single photon emission computed tomograms were superimposed on X-ray computed tomograms to assess topographically the perfusion of the entire brain. Study of cerebrovascular diseases using this method showed: (1) regional cerebral blood flow change; (2) perfusion distribution change; (3) the route by which blood reached the brain or the obstructed artery proximal to the circle of Willis; (4) development of a collateral system and its actual function; and (5) efficacy of surgical bypass after extracranial-intracranial anastomosis. This method is especially useful in hemodynamic assessment in patients with ischemic cerebrovascular disease.
对25例脑血管疾病患者采用选择性连续注入氪-81m（Kr-81m）的方法进行了局部脑血流和血液动力学的断层扫描研究。将Kr-81m单光子发射计算机断层扫描图与X射线计算机断层扫描图叠加，以从地形学角度评估整个大脑的灌注情况。使用该方法对脑血管疾病的研究显示：（1）局部脑血流变化；（2）灌注分布变化；（3）血液到达大脑的途径或 Willis 环近端阻塞的动脉；（4）侧支循环系统的形成及其实际功能；以及（5）颅外-颅内吻合术后外科搭桥的疗效。该方法在缺血性脑血管疾病患者的血液动力学评估中特别有用。
