Pyykkö I, Dahlen A I, Henriksson N G, Juhola M
Acta Otolaryngol. 1984 Sep-Oct;98(3-4):279-86. doi: 10.3109/00016488409107564.
Postrotatory responses of nystagmus were analysed in an exponential model by utilizing linear regression analysis. Four nystagmus qualities (velocity and duration of slow and fast phases) were studied in 10 patients with vestibular peripheral lesions, 10 patients with frontal lobe lesions and 10 patients with brain-stem lesions, together with 10 control subjects. In addition, pauses during the responses were quantified. Patients with frontal lobe lesions differed from other groups by scoring higher values of slow phase velocity and by exhibiting more pauses. The time constant was significantly shorter in patients with brain-stem lesion than in any other group. As regards other qualities, e.g. slow phase duration and fast phase velocity, or duration, no differences were observed. The pathological dysrhythmia may therefore be presented as changes in the gain and time constant of slow phase velocity as well as in pauses during nystagmus. Since all these changes may be encountered in normal subjects, one should be cautious in interpreting these changes as being pathological in each individual case.
通过线性回归分析，利用指数模型对眼震的旋转后反应进行了分析。在10例前庭周围性病变患者、10例额叶病变患者、10例脑干病变患者以及10名对照受试者中，研究了四种眼震特征（慢相和快相的速度及持续时间）。此外，对反应过程中的停顿进行了量化。额叶病变患者与其他组不同，其慢相速度得分较高且停顿更多。脑干病变患者的时间常数明显短于其他任何组。至于其他特征，如慢相持续时间、快相速度或持续时间，则未观察到差异。因此，病理性心律失常可能表现为慢相速度的增益和时间常数以及眼震期间停顿的变化。由于所有这些变化在正常受试者中也可能出现，因此在将这些变化解释为每个个体的病理性变化时应谨慎。
