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春季结膜炎患者泪液和血清中的变应原特异性免疫球蛋白E抗体。

Allergen-specific immunoglobulin E antibodies in tears and serum of vernal conjunctivitis patients.

作者信息

Sompolinsky D, Samra Z, Zavaro A, Barishak Y

出版信息

Int Arch Allergy Appl Immunol. 1984;75(4):317-21. doi: 10.1159/000233640.

DOI:10.1159/000233640
PMID:6334034
Abstract

Tears and sera of 53 patients of vernal conjunctivitis were examined for antibodies of the IgE type to a panel of 18 allergens. In 18 of the patients (34.0%) allergen-specific IgE was demonstrated in both tears and serum, in 3 (5.7%) in tears only, and in 4 (7.5%) in serum only. The antigen-specific reactions with tear fluid were found in patients with the highest total IgE levels, not only in tears but also in serum. This is evidence for a specific, local allergic reaction in these patients. Most positive reactions were to perennial allergens, particularly house dust mites, cat epithelium and Bermuda grass. This fact is in harmony with the lack of season-linked symptoms in most patients in this geographical area.

摘要

对53例春季结膜炎患者的眼泪和血清进行检测,以检测针对18种过敏原的IgE型抗体。18例患者(34.0%)眼泪和血清中均检测到过敏原特异性IgE,3例(5.7%)仅在眼泪中检测到,4例(7.5%)仅在血清中检测到。泪液中抗原特异性反应见于总IgE水平最高的患者,不仅在眼泪中,血清中也是如此。这证明这些患者存在特异性局部过敏反应。大多数阳性反应针对常年性过敏原,尤其是屋尘螨、猫上皮和百慕大草。这一事实与该地理区域大多数患者缺乏季节性相关症状相符。

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Eosinophil cationic protein in tears in allergic conjunctivitis.过敏性结膜炎患者泪液中的嗜酸性粒细胞阳离子蛋白
Br J Ophthalmol. 1996 Jun;80(6):556-60. doi: 10.1136/bjo.80.6.556.
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In vitro assays for immunoglobulin E. Methodology, indications, and interpretation.免疫球蛋白E的体外检测。方法、适应证及解读
Clin Rev Allergy. 1988 Summer;6(2):93-139. doi: 10.1007/BF02914935.