Job J S, John T J, Joseph A
Bull World Health Organ. 1984;62(5):737-41.
Antibody response to measles vaccine was measured in 238 subjects aged 6-15 months. Seroconversion rates ranged from 74% at 6 months of age to 100% at 13-15 months; the differences in age-specific rates were not statistically significant. The postimmunization antibody titres increased with increasing age of the vaccinee. Seroconversion rates and antibody titres in 49 subjects with grades I and II malnutrition were not significantly different from those in the 189 normal subjects.These results support the recommendation of 9 months as a satisfactory age for commencement of measles immunization in India. However, the highest antibody levels and seroconversion rates were obtained in children over 12 months of age.
对238名6至15个月大的受试者测量了对麻疹疫苗的抗体反应。血清转化率从6个月大时的74%到13 - 15个月大时的100%不等；特定年龄组的比率差异无统计学意义。接种疫苗后的抗体滴度随着接种者年龄的增加而升高。49名患有I级和II级营养不良的受试者的血清转化率和抗体滴度与189名正常受试者的血清转化率和抗体滴度无显著差异。这些结果支持了在印度将9个月作为开始麻疹免疫的适宜年龄的建议。然而，12个月以上儿童获得了最高的抗体水平和血清转化率。
