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儿童系统性葡萄膜炎综合征:340例分析

Systemic uveitis syndromes in childhood: an analysis of 340 cases.

作者信息

Kanski J J, Shun-Shin G A

出版信息

Ophthalmology. 1984 Oct;91(10):1247-52. doi: 10.1016/s0161-6420(84)34177-x.

DOI:10.1016/s0161-6420(84)34177-x
PMID:6334829
Abstract

Three hundred forty patients with anterior uveitis associated with a specific systemic disease are described. All patients developed uveitis or the systemic disease, or both, prior to the age of 16 years, By far the most frequent systemic disorder was a sero-negative arthritis. Others included sarcoidosis, Behçet's disease, the Vogt-Koyanagi-Harada syndrome, and arteritis. Children with pauciarticular juvenile chronic arthritis, especially when associated with antinuclear antibodies, are at particular risk of developing chronic uveitis and they should be screened at frequent intervals, even if asymptomatic. Treatment of secondary cataracts in children using vitreous cutters usually gives good results. The most devastating complication of chronic uveitis is secondary glaucoma.

摘要

本文描述了340例与特定全身性疾病相关的前葡萄膜炎患者。所有患者在16岁之前均出现了葡萄膜炎或全身性疾病,或两者皆有。迄今为止,最常见的全身性疾病是血清阴性关节炎。其他疾病包括结节病、白塞病、小柳原田综合征和动脉炎。患有少关节型幼年慢性关节炎的儿童,尤其是伴有抗核抗体的儿童,发生慢性葡萄膜炎的风险特别高,即使无症状也应定期进行筛查。使用玻璃体切割器治疗儿童继发性白内障通常效果良好。慢性葡萄膜炎最严重的并发症是继发性青光眼。

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Systemic uveitis syndromes in childhood: an analysis of 340 cases.儿童系统性葡萄膜炎综合征:340例分析
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Jack J. Kanski (1939-2019)-the prominent educator in ophthalmology.
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