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尿阳离子与血压——人群研究

Urinary cations and blood pressure--population studies.

作者信息

Kesteloot H

出版信息

Ann Clin Res. 1984;16 Suppl 43:72-80.

PMID:6336027
Abstract

The relationship between urinary cations and blood pressure has been examined by means of multiple regression analysis with the inclusion of age, BMI, urinary 24-hour creatinine, heart rate and the 24-hour urinary excretion of Na, K and, in a subsample, of Ca and Mg. In Korea where the Na intake is high and the K intake is low a significant positive relationship was found between 24-hour urinary Na and blood pressure and a negative one between 24-hour urinary K and blood pressure. In Belgium, however, a negative relationship was found between 24-hour urinary Na and the Na/K ratio and blood pressure. In a subsample the 24-hour urinary Mg excretion significantly and negatively correlated with diastolic blood pressure both in men (slope -0.245 mm Hg/mmol Mg) and in women (slope -0.525 mm Hg/mmol Mg) while no significant relationship was found with 24-hour urinary Ca. Further study of the importance of Mg for blood pressure regulation is warranted.

摘要

通过多元回归分析研究了尿阳离子与血压之间的关系,分析中纳入了年龄、体重指数、24小时尿肌酐、心率以及24小时尿钠、钾排泄量,在一个子样本中还纳入了钙和镁的24小时尿排泄量。在钠摄入量高而钾摄入量低的韩国,发现24小时尿钠与血压之间存在显著正相关,24小时尿钾与血压之间存在负相关。然而,在比利时,24小时尿钠、钠/钾比值与血压之间呈负相关。在一个子样本中,24小时尿镁排泄量与男性(斜率为-0.245 mmHg/mmol镁)和女性(斜率为-0.525 mmHg/mmol镁)的舒张压均呈显著负相关,而与24小时尿钙未发现显著关系。有必要进一步研究镁对血压调节的重要性。

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引用本文的文献

1
Relation of urinary calcium and magnesium excretion to blood pressure: The International Study Of Macro- And Micro-nutrients And Blood Pressure and The International Cooperative Study On Salt, Other Factors, And Blood Pressure.尿钙和镁排泄与血压的关系:国际微量营养素与血压研究和国际盐与其他因素合作研究。
Am J Epidemiol. 2011 Jul 1;174(1):44-51. doi: 10.1093/aje/kwr049. Epub 2011 May 30.
2
By how much does dietary salt reduction lower blood pressure? I--Analysis of observational data among populations.饮食中减少盐的摄入量能使血压降低多少?I——人群中观察性数据的分析。
BMJ. 1991 Apr 6;302(6780):811-5. doi: 10.1136/bmj.302.6780.811.