Kulla H G
J Bacteriol. 1983 Jan;153(1):546-9. doi: 10.1128/jb.153.1.546-549.1983.
Citrate lyase, the key enzyme of anaerobic citrate catabolism, could not be deleted from Salmonella typhimurium. The only class of mutants found had a mode of covalent regulation that strongly resembled the Escherichia coli system: citrate lyase was only active, i.e., acetylated, when a cosubstrate was present.
柠檬酸裂解酶是厌氧柠檬酸分解代谢的关键酶,无法从鼠伤寒沙门氏菌中删除。发现的唯一一类突变体具有一种共价调节模式,与大肠杆菌系统极为相似:只有当存在共底物时,柠檬酸裂解酶才具有活性,即被乙酰化。