Silverman D E, Stamey T A
Medicine (Baltimore). 1983 Jan;62(1):44-51. doi: 10.1097/00005792-198301000-00004.
In summary, 46 renal lithotomies were performed in 40 patients for struvite infection stones. All patients had documented urinary tract infections at the time of surgery; all stones were cultured, demonstrated to contain bacteria and proved crystallographically to be composed primarily of struvite with smaller amounts of apatite. The recurrence rate in a mean followup period of 7 years was 2.5% (one patient). The negligible recurrence rate emphasizes that struvite stones are caused by urea-splitting bacteria, rather than metabolic disorders, and that a comprehensive approach that emphasizes biochemical, bacteriologic, and roentgenographic techniques is more important than the type of surgical procedure used to remove the stones. We believe that our routine of leaving a small polyethylene nephrostomy tube in every patient, combined with postoperative plain-film tomograms regardless of the results of intraoperative radiography, and the liberal use of hemiacidrin irrigation to dissolve any residual struvite particles with their entrapped bacteria, accounts for the virtual absence of stone recurrences in our series.
总之,对40例患者进行了46次肾切开取石术,以治疗鸟粪石感染性结石。所有患者在手术时均有记录在案的尿路感染;所有结石均进行了培养,证明含有细菌,并经晶体学证实主要由鸟粪石组成,还有少量磷灰石。平均随访7年的复发率为2.5%(1例患者)。可忽略不计的复发率强调鸟粪石结石是由尿素分解细菌引起的,而非代谢紊乱,并且强调生化、细菌学和X线检查技术的综合方法比用于去除结石的手术方式更为重要。我们认为,我们在每位患者中常规留置一根小的聚乙烯肾造瘘管,无论术中影像学检查结果如何,术后均进行平片断层摄影,以及大量使用半胱氨酸冲洗以溶解任何残留的鸟粪石颗粒及其包裹的细菌,这就是我们系列研究中结石几乎无复发的原因。