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肺炎克雷伯菌中nifA基因产物对氮代谢基因的调控

Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae.

作者信息

Ow D W, Ausubel F M

出版信息

Nature. 1983 Jan 27;301(5898):307-13. doi: 10.1038/301307a0.

DOI:10.1038/301307a0
PMID:6337346
Abstract

The Klebsiella pneumoniae nifA gene product, which is known to activate expression of the nitrogen fixation (nif) structural genes, is shown here also to be able to substitute for the product of the gene glnG (ntrC) in the regulation of other nitrogen metabolism genes. An evolutionary relationship between the nifA and glnG genes is suggested.

摘要

肺炎克雷伯菌的nifA基因产物,已知其可激活固氮(nif)结构基因的表达,本文还表明它在调控其他氮代谢基因时能够替代glnG(ntrC)基因的产物。这表明nifA基因与glnG基因之间存在进化关系。

相似文献

1
Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae.肺炎克雷伯菌中nifA基因产物对氮代谢基因的调控
Nature. 1983 Jan 27;301(5898):307-13. doi: 10.1038/301307a0.
2
Nitrogen control of the nif regulon in Klebsiella pneumoniae: involvement of the ntrA gene and analogies between ntrC and nifA.肺炎克雷伯菌中固氮基因簇的氮调控:ntrA基因的作用以及ntrC与nifA之间的相似性
EMBO J. 1983;2(1):39-44. doi: 10.1002/j.1460-2075.1983.tb01377.x.
3
Mutational analysis of the Klebsiella pneumoniae nitrogenase promoter: sequences essential for positive control by nifA and ntrC (glnG) products.肺炎克雷伯菌固氮酶启动子的突变分析:nifA和ntrC(glnG)产物进行正调控所必需的序列。
J Bacteriol. 1985 Mar;161(3):868-74. doi: 10.1128/jb.161.3.868-874.1985.
4
Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter.肺炎克雷伯菌nifA产物激活苜蓿根瘤菌固氮酶启动子。
Nature. 1983 Feb 24;301(5902):728-32. doi: 10.1038/301728a0.
5
Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae.肺炎克雷伯菌中nifLA启动子的正调控与自身调控
Nature. 1983 Jan 27;301(5898):302-7. doi: 10.1038/301302a0.
6
Nitrogen fixation specific regulatory genes of Klebsiella pneumoniae and Rhizobium meliloti share homology with the general nitrogen regulatory gene ntrC of K. pneumoniae.肺炎克雷伯菌和苜蓿根瘤菌的固氮特异性调控基因与肺炎克雷伯菌的一般氮调控基因ntrC具有同源性。
Nucleic Acids Res. 1985 Jun 25;13(12):4539-55. doi: 10.1093/nar/13.12.4539.
7
Activation of nif gene expression in Azotobacter by the nifA gene product of Klebsiella pneumoniae.肺炎克雷伯菌的nifA基因产物激活固氮菌中nif基因的表达。
Nature. 1983;301(5901):626-8. doi: 10.1038/301626a0.
8
Promoters regulated by the glnG (ntrC) and nifA gene products share a heptameric consensus sequence in the -15 region.受glnG(ntrC)和nifA基因产物调控的启动子在-15区域共享一个七聚体共有序列。
Proc Natl Acad Sci U S A. 1983 May;80(9):2524-8. doi: 10.1073/pnas.80.9.2524.
9
Positive and negative control of the glnA ntrBC regulon in Klebsiella pneumoniae.肺炎克雷伯菌中谷氨酰胺合成酶基因(glnA)ntrBC调控子的正调控与负调控
EMBO J. 1984 Mar;3(3):501-7. doi: 10.1002/j.1460-2075.1984.tb01837.x.
10
Effect of nifA product on suppression of Nif- phenotype of gln mutation and constitutive synthesis of nitrogenase in Klebsiella pneumoniae.肺炎克雷伯菌中nifA产物对谷氨酰胺突变体Nif-表型抑制及固氮酶组成型合成的影响。
Sci Sin B. 1983 Dec;26(12):1258-68.

引用本文的文献

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Mol Gen Genet. 1987 Oct;209(3):621-6. doi: 10.1007/BF00331174.
2
Bioluminescence in soybean root nodules: Demonstration of a general approach to assay gene expression in vivo by using bacterial luciferase.大豆根瘤中的生物发光:利用细菌荧光素酶检测体内基因表达的一般方法的验证。
Proc Natl Acad Sci U S A. 1986 Dec;83(23):9080-4. doi: 10.1073/pnas.83.23.9080.
3
Cloning of the symbiotic region of Rhizobium leguminosarum: the nodulation genes are between the nitrogenase genes and a nifA-like gene.
根瘤菌共生区的克隆:结瘤基因位于固氮酶基因和一个类似于 nifA 的基因之间。
EMBO J. 1983;2(6):947-52. doi: 10.1002/j.1460-2075.1983.tb01526.x.
4
The pleiotropic nature of symbiotic regulatory mutants: Bradyrhizobium japonicum nifA gene is involved in control of nif gene expression and formation of determinate symbiosis.共生调控突变体的多效性本质:日本慢生根瘤菌nifA基因参与固氮基因表达的调控以及定型共生的形成。
EMBO J. 1986 Jun;5(6):1165-73. doi: 10.1002/j.1460-2075.1986.tb04342.x.
5
A promoter region binding protein and DNA gyrase regulate anaerobic transcription of nifLA in Enterobacter cloacae.一种启动子区域结合蛋白和DNA促旋酶调节阴沟肠杆菌中nifLA的厌氧转录。
J Bacteriol. 2000 Jul;182(14):3920-3. doi: 10.1128/JB.182.14.3920-3923.2000.
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Virulence of the phytopathogen Pseudomonas syringae pv. maculicola is rpoN dependent.植物病原体丁香假单胞菌番茄致病变种的毒力依赖于rpoN。
J Bacteriol. 2000 Jun;182(12):3498-507. doi: 10.1128/JB.182.12.3498-3507.2000.
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A- and T-tract-mediated intrinsic curvature in native DNA between the binding site of the upstream activator NtrC and the nifLA promoter of Klebsiella pneumoniae facilitates transcription.肺炎克雷伯菌上游激活因子NtrC的结合位点与nifLA启动子之间天然DNA中由A序列和T序列介导的内在曲率促进转录。
J Bacteriol. 1999 Sep;181(17):5296-302. doi: 10.1128/JB.181.17.5296-5302.1999.
8
Iron is required to relieve inhibitory effects on NifL on transcriptional activation by NifA in Klebsiella pneumoniae.肺炎克雷伯菌中,需要铁来解除NifL对NifA转录激活的抑制作用。
J Bacteriol. 1996 Aug;178(15):4679-87. doi: 10.1128/jb.178.15.4679-4687.1996.
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Arch Microbiol. 1993;159(3):276-81. doi: 10.1007/BF00248484.