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肺炎克雷伯菌中nifLA启动子的正调控与自身调控

Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae.

作者信息

Drummond M, Clements J, Merrick M, Dixon R

出版信息

Nature. 1983 Jan 27;301(5898):302-7. doi: 10.1038/301302a0.

DOI:10.1038/301302a0
PMID:6337345
Abstract

The nitrogen fixation (nif) genes of Klebsiella pneumoniae are specifically regulated by the products of the nifLA operon. We have located the promoter of this operon, and identified sequences required for nifLA transcription. Transcription from this promoter is shown to be positively regulated by the ntrC gene product (which coordinates the expression of many operons required for nitrogen assimilation) and also autogenously by the product of the nifA gene.

摘要

肺炎克雷伯菌的固氮(nif)基因受nifLA操纵子产物的特异性调控。我们已定位该操纵子的启动子,并鉴定出nifLA转录所需的序列。该启动子的转录显示受ntrC基因产物(它协调许多氮同化所需操纵子的表达)正向调控,也受nifA基因产物自身调控。

相似文献

1
Positive control and autogenous regulation of the nifLA promoter in Klebsiella pneumoniae.肺炎克雷伯菌中nifLA启动子的正调控与自身调控
Nature. 1983 Jan 27;301(5898):302-7. doi: 10.1038/301302a0.
2
The use of cloned nif (nitrogen fixation) DNA to investigate transcriptional regulation of nif expression in Klebsiella pneumoniae.利用克隆的固氮基因(nif)DNA研究肺炎克雷伯菌中nif表达的转录调控。
Mol Gen Genet. 1981;184(1):102-6. doi: 10.1007/BF00271203.
3
Requirements for transcriptional activation in vitro of the nitrogen-regulated glnA and nifLA promoters from Klebsiella pneumoniae: dependence on activator concentration.肺炎克雷伯菌氮调节的谷氨酰胺合成酶基因(glnA)和固氮调节基因(nifLA)启动子体外转录激活的要求:对激活剂浓度的依赖性
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In vitro transcription of the nitrogen fixation regulatory operon nifLA of Klebsiella pneumoniae.肺炎克雷伯菌固氮调节操纵子nifLA的体外转录
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Positive and negative control of the glnA ntrBC regulon in Klebsiella pneumoniae.肺炎克雷伯菌中谷氨酰胺合成酶基因(glnA)ntrBC调控子的正调控与负调控
EMBO J. 1984 Mar;3(3):501-7. doi: 10.1002/j.1460-2075.1984.tb01837.x.
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Klebsiella pneumoniae nifA product activates the Rhizobium meliloti nitrogenase promoter.肺炎克雷伯菌nifA产物激活苜蓿根瘤菌固氮酶启动子。
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Mutational analysis of the Klebsiella pneumoniae nitrogenase promoter: sequences essential for positive control by nifA and ntrC (glnG) products.肺炎克雷伯菌固氮酶启动子的突变分析:nifA和ntrC(glnG)产物进行正调控所必需的序列。
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Nitrogen control of the nif regulon in Klebsiella pneumoniae: involvement of the ntrA gene and analogies between ntrC and nifA.肺炎克雷伯菌中固氮基因簇的氮调控:ntrA基因的作用以及ntrC与nifA之间的相似性
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Transcriptional analysis of promoter mutations in the Klebsiella pneumoniae nifHDKY operon.肺炎克雷伯菌固氮酶操纵子启动子突变的转录分析
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10
Regulation of nitrogen metabolism genes by nifA gene product in Klebsiella pneumoniae.肺炎克雷伯菌中nifA基因产物对氮代谢基因的调控
Nature. 1983 Jan 27;301(5898):307-13. doi: 10.1038/301307a0.

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Mol Gen Genet. 1987 Oct;209(3):621-6. doi: 10.1007/BF00331174.
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Proc Natl Acad Sci U S A. 1986 Dec;83(23):9080-4. doi: 10.1073/pnas.83.23.9080.
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Proc Natl Acad Sci U S A. 1986 Mar;83(6):1757-61. doi: 10.1073/pnas.83.6.1757.
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