用抗IgD血清对小鼠进行预处理不会导致对由三硝基苯 - 抗原提取细胞基质 - 聚蔗糖（TNP - AECM - Ficoll）或脂多糖诱导的免疫反应性的抑制。
Pretreatment of mice with anti-IgD serum does not result in suppression of immune responsiveness induced by TNP-AECM-Ficoll or lipopolysaccharide.
作者信息
Dresser D W, Parkhouse R M, Popham A M
出版信息
Immunology. 1983 Mar;48(3):497-501.
Unlike the suppression of a primary response to a thymus-dependent antigen, pretreatment of mice with anti-IgD serum has no effect on the response to a thymus-independent (TI) antigen. It has also been shown that anti-IgD serum injected parenterally into mice 2 days previously, has no suppressive effect on non-specific responsiveness to an intraperitoneal injection of LPS. There is a similar lack of effect on the non-specific element of responsiveness to a TI antigen. These results provide in vivo confirmation of the results of previous in vitro experimentation.
与对胸腺依赖性抗原的初次应答受到抑制不同，用抗IgD血清对小鼠进行预处理，对其对胸腺非依赖性（TI）抗原的应答没有影响。研究还表明，提前2天经肠胃外途径给小鼠注射抗IgD血清，对腹腔注射LPS的非特异性应答没有抑制作用。对TI抗原应答的非特异性成分也同样没有影响。这些结果为之前体外实验的结果提供了体内验证。
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