Kondrat'eva T K, Novikova T K, Fontalin L N, Kondrat'eva I A, Blandova Z K
Biull Eksp Biol Med. 1983 Mar;95(3):73-5.
The nature of cells responsible for the genetic resistance of lethally irradiated CBA mice to lymphocytes of (CBA x M523)F1 hybrids was studied. Preirradiation of the hosts was shown to abolish the resistance. The latter was generally recovered by syngeneic thymocytes or splenocytes while embryonic liver and bone marrow cells or splenocytes treated with anti-Thy-I serum plus complement before injection into host were ineffective. It is postulated that some cells with T cell characteristics are responsible for the phenomenon of parental resistance. These cells differ in several respects from T cells that mediate the transplantation immunity and from M cells that control other forms of the genetic resistance.
研究了对致死剂量照射的CBA小鼠对（CBA×M523）F1杂种淋巴细胞的遗传抗性负责的细胞的性质。结果表明，宿主的预照射可消除抗性。同基因胸腺细胞或脾细胞通常可恢复抗性，而胚胎肝和骨髓细胞或在注入宿主前用抗Thy-1血清加补体处理的脾细胞则无效。据推测，一些具有T细胞特征的细胞负责亲本抗性现象。这些细胞在几个方面不同于介导移植免疫的T细胞和控制其他形式遗传抗性的M细胞。
