Soss T L
Laryngoscope. 1983 Apr;93(4):408-9. doi: 10.1002/lary.1983.93.4.408.
Otolaryngologic allergy concerns itself greatly with the teachings and influence of the late French Hansel, M.D., and his principles of optimal dosage. Later Herbert Rinkel, M.D., was to contribute the titration technique which allowed for a more systematic administration of antigens. Other areas such as provocative testing for foods as well as more controversial areas were later developed. These included cytotoxic testing as well as emphasis on clinical ecology techniques. The otolaryngologist has been equipped to handle all phases of nasal problems including allergy by 1. management of obvious surgical problems, 2. symptomatic approach with medical methods, 3. environmental controls when indicated and 4. immunotherapy. The last method includes titration as well as radioimmunoassay techniques (RAST). The author's conjecture regarding the future direction of allergy management from the otolaryngologist's view point is also given. Personal observations and anecdotes of some of the pioneers in the field are included.
耳鼻喉科过敏领域十分关注已故法国医学博士汉塞尔的学说和影响，以及他的最佳剂量原则。后来，医学博士赫伯特·林克尔贡献了滴定技术，该技术能更系统地给予抗原。其他领域，如食物激发试验以及更具争议性的领域，后来也得到了发展。这些领域包括细胞毒性试验以及对临床生态学技术的重视。耳鼻喉科医生已具备处理鼻部问题各个阶段（包括过敏）的能力，方法如下：1. 处理明显的外科问题；2. 采用药物方法缓解症状；3. 在必要时进行环境控制；4. 进行免疫疗法。最后一种方法包括滴定以及放射免疫分析技术（RAST）。文中还给出了作者从耳鼻喉科医生的角度对过敏管理未来方向的推测。此外，还收录了该领域一些先驱者的个人观察和轶事。
