Kirchner R, Kalbfleisch H, Hort W
Leber Magen Darm. 1978 Apr;8(2):74-7.
Livers of two patients suffering from cirrhosis were weighed at post mortem, and found to have weights of 510 resp. 640 g. The quantity of hepatocytes was measured histometrically and estimated to be approx. 210 g in both patients; this means, that total liver mass in these patients was reduced to approximately 30% of normal, and that hepatic insufficiency had been incumbent in both of these patients. Difficulties in the methods of measuring the quantity of normal liver parenchyma in cirrhotic livers are discussed. Initiation of hepatic coma in liver cirrhosis is dependent in the first place, but not exclusively, upon the degree of reduction of liver parenchyma.
对两名肝硬化患者的肝脏在尸检时进行称重,发现重量分别为510克和640克。通过组织测量法测定肝细胞数量,估计两名患者的肝细胞数量均约为210克;这意味着,这些患者的肝脏总质量降至正常的约30%,且两名患者均存在肝功能不全。文中讨论了测量肝硬化肝脏中正常肝实质数量方法的难点。肝硬化中肝昏迷的引发首先(但并非唯一)取决于肝实质减少的程度。