Schubert G E, Bethke-Bedürftig B A, Bujnoch A W, Diem A
Z Gastroenterol. 1982 Apr;20(4):221-7.
Post mortems of 2289 patients with liver cirrhosis revealed that 37% died of causes related directly to cirrhosis i.e. liver failure or hemorrhage from oesophageal varices. Patients who died of ruptured oesophageal varices in 82% have splenomegaly and most frequently hepatomegaly. Livercell carcinomas were recognized in 7,5% of cirrhotic livers, increasing to 10% in 1976-1978. This rise particularly is conspicuous in women. Liver carcinoma is 4,5 times more frequent in postnecrotic than in portal cirrhosis.
对2289例肝硬化患者进行的尸检显示,37%的患者死于与肝硬化直接相关的原因,即肝衰竭或食管静脉曲张出血。死于食管静脉曲张破裂的患者中,82%有脾肿大,且最常见的是肝肿大。在7.5%的肝硬化肝脏中发现了肝细胞癌,在1976 - 1978年这一比例增至10%。这种上升在女性中尤为明显。坏死后肝硬化患者患肝癌的几率是门脉性肝硬化患者的4.5倍。