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大鼠脂肪细胞中S-100蛋白的免疫化学和免疫细胞化学研究

Immunochemical and immunocytochemical study of S-100 protein in rat adipocytes.

作者信息

Michetti F, Dell'Anna E, Tiberio G, Cocchia D

出版信息

Brain Res. 1983 Mar 7;262(2):352-6. doi: 10.1016/0006-8993(83)91032-6.

DOI:10.1016/0006-8993(83)91032-6
PMID:6340793
Abstract

S-100 is a protein originally believed to be unique to the nervous system. We report here on the presence of S-100 in rat adipocytes, using immunohistochemical and immunochemical methods. We demonstrate that the protein in adipose tissue is present at a concentration comparable to that measured in the nervous tissue and is immunologically identical to brain S-100, indicating that the protein can no longer be regarded as being specific to the nervous system.

摘要

S - 100是一种最初被认为是神经系统所特有的蛋白质。我们在此报告使用免疫组织化学和免疫化学方法在大鼠脂肪细胞中发现了S - 100。我们证明,脂肪组织中的这种蛋白质浓度与在神经组织中测得的浓度相当,并且在免疫上与脑S - 100相同,这表明该蛋白质不能再被视为神经系统所特有。

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