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急性肠胃炎的白细胞分类计数。早期诊断的辅助手段。

Differential leukocyte count in acute gastroenteritis. An aid to early diagnosis.

作者信息

Ashkenazi S, Amir Y, Dinari G, Schonfeld T, Nitzan M

出版信息

Clin Pediatr (Phila). 1983 May;22(5):356-8. doi: 10.1177/000992288302200506.

DOI:10.1177/000992288302200506
PMID:6340905
Abstract

The total and differential leukocyte counts of 238 infants with acute gastroenteritis were evaluated as an aid in differentiating between nonbacterial and bacterial infection. In contrast to the total leukocyte count, which was noncontributory, the absolute band count and the ratio between band and total neutrophil count (B/N ratio) were helpful, with the highest values seen in patients with Shigellosis. A B/N ratio greater than 0.10 can help differentiate Shigella, Salmonella, and Campylobacter infections from E. coli and nonbacterial gastroenteritis with a sensitivity of 84.3 per cent and a specificity of 74.5 per cent.

摘要

对238例急性胃肠炎婴儿的白细胞总数及分类计数进行评估,以辅助鉴别非细菌性感染和细菌性感染。与无诊断价值的白细胞总数不同,绝对杆状核细胞计数以及杆状核细胞与中性粒细胞总数之比(B/N比)具有诊断价值,其中志贺菌病患者的这些指标值最高。B/N比大于0.10有助于鉴别志贺菌、沙门菌和弯曲杆菌感染与大肠杆菌感染及非细菌性胃肠炎,其敏感性为84.3%,特异性为74.5%。

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Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function.
肠致病性大肠杆菌(EPEC)在破坏上皮屏障功能之前会使先天免疫反应失活。
Cell Microbiol. 2007 Aug;9(8):1909-21. doi: 10.1111/j.1462-5822.2007.00923.x. Epub 2007 Mar 26.
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Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed.福氏志贺菌被困于多形核白细胞液泡中并被有效杀灭。
Infect Immun. 1997 Jan;65(1):110-5. doi: 10.1128/iai.65.1.110-115.1997.