Adgey A A, Campbell N P, Webb S W, Kennedy A L, Pantridge J F
Med Instrum. 1978 Jan-Feb;12(1):17-9.
Since the lower the energy used, the less the possible myocardial damage, two studies of 214 patients in ventricular fibrillation (VF) were conducted, using two types of defibrillators each charged to 200 Wsec and 100Wsec. In the first study, each defibrillator was charged to 200 Wsec (150-165 Wsec delivered). Up to three 200-Wsec shocks successfully converted 222 of 233 VF episodes. In 199 episodes, a single shock successfully removed the fibrillation. In 48 episodes in patients weighing more than 80 kg, VF was removed in 43 (90 percent). In the second study, from a stored energy of 100 Wsec, 74 to 82 Wsec of energy were delivered in the initial shock to treat 161 VF episodes in 94 patients. The first shock was successful in 101 (63 percent) of the 161 episodes. Up to three 100-Wsec shocks achieved 81 percent conversion in 52 episodes. A third 100-Wsec shock seldom succeeded. Using a sequence of 100 - 200 - 400 Wsec shocks, 93 (91 percent) of 102 episodes were successfully converted. There was not a single instance of failure to remove VF among the 214 patients with a maximal delivered energy of 330 Wsec. Thus, the direction towards the production of larger instruments storing more than 400 Wsec energy seems unwarranted.
由于使用的能量越低,心肌受损的可能性就越小,因此对214名心室颤动(VF)患者进行了两项研究,分别使用两种类型的除颤器,每种除颤器的充电能量分别为200瓦秒和100瓦秒。在第一项研究中,每个除颤器充电至200瓦秒(释放能量为150 - 165瓦秒)。高达三次200瓦秒的电击成功转复了233次VF发作中的222次。在199次发作中,单次电击成功消除了颤动。在体重超过80公斤的患者的48次发作中,43次(90%)的VF被消除。在第二项研究中,从100瓦秒的储能开始,首次电击释放74至82瓦秒的能量,以治疗94名患者的161次VF发作。161次发作中的101次(63%)首次电击成功。高达三次100瓦秒的电击在52次发作中实现了81%的转复率。第三次100瓦秒的电击很少成功。使用100 - 200 - 400瓦秒的电击序列,102次发作中的93次(91%)成功转复。在214名患者中,最大释放能量为330瓦秒,没有一例未能消除VF。因此,生产储存能量超过400瓦秒的大型仪器的方向似乎没有必要。