Kincaid M C, Green W R
Surv Ophthalmol. 1983 Jan-Feb;27(4):211-32. doi: 10.1016/0039-6257(83)90123-6.
Leukemia may involve almost any ocular tissue, by direct infiltration, by hemorrhage, and by ischemic changes. Both acute and chronic leukemia can cause ocular signs, either initially or later in the disease process; the clinical features and pathologic correlations of this involvement are reviewed. Also, various chemotherapeutic agents used to treat leukemia may cause ocular toxicity. Recently, bone marrow transplants have been performed more frequently in an attempt to prolong patient survival; if graft-versus-host disease results, one symptom is dry eyes from alacrima. Superimposed infection due to immunosuppression can occur from the disease itself or from treatment. Recognition by the ophthalmologist of the various ocular signs is important in assessing the course and prognosis of leukemia.
白血病可通过直接浸润、出血及缺血性改变累及几乎任何眼部组织。急性和慢性白血病均可在疾病过程的初期或后期引起眼部体征；本文将对这种累及的临床特征及病理关联进行综述。此外，用于治疗白血病的各种化疗药物可能会导致眼部毒性。近来，为延长患者生存期，骨髓移植的实施更为频繁；若发生移植物抗宿主病，其中一个症状是因泪腺分泌减少而导致干眼。免疫抑制所致的叠加感染可源于疾病本身或治疗过程。眼科医生识别各种眼部体征对于评估白血病的病程及预后很重要。
