Suppr超能文献

一种新型三卤代皮质类固醇(卤米松)与二丙酸倍他米松的比较临床试验

[Comparative clinical trial of a new trihalogenated dermatocorticoid (halometasone) versus betamethasone dipropionate].

作者信息

Schuppli R, Dressler H, Yawalkar S J, Weirich E G

出版信息

Z Hautkr. 1983 Feb 15;58(4):230-7.

PMID:6342285
Abstract

In a multicenter controlled study carried out in Austria and Switzerland by 8 dermatologists in 208 patients with acute eczematous dermatoses, 0.05% halometasone cream proved to have significantly superior clinical efficacy than 0.05% betamethasone dipropionate cream (P much less than 0.05) showing an equal tolerability. Good to very good results were reported in 93% of the patients treated with halometasone and in 84% of those treated with betamethasone dipropionate creams (Diprosone, Diproderm). General tolerability of both treatments was good. Neither skin atrophy nor any systemic adverse effect, due to the transcutaneous absorption of the corticoids, were observed in this study.

摘要

在奥地利和瑞士由8位皮肤科医生对208例急性湿疹性皮炎患者开展的一项多中心对照研究中,0.05%卤米松乳膏被证明临床疗效显著优于0.05%丙酸倍他米松乳膏(P远小于0.05),且耐受性相当。使用卤米松治疗的患者中有93%报告疗效良好至非常好,使用丙酸倍他米松乳膏(得宝松、特美肤)治疗的患者中有84%报告疗效良好至非常好。两种治疗的总体耐受性良好。本研究中未观察到因皮质类固醇经皮吸收导致的皮肤萎缩或任何全身不良反应。

相似文献

引用本文的文献

1
Topical anti-inflammatory treatments for eczema: network meta-analysis.外用抗炎治疗湿疹:网状荟萃分析。
Cochrane Database Syst Rev. 2024 Aug 6;8(8):CD015064. doi: 10.1002/14651858.CD015064.pub2.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验