Watts K C, Boyo-Ekwueme H, To A, Posnansky M, Coleman D V
Acta Cytol. 1983 Jan-Feb;27(1):38-44.
Cytogenetic analysis was used to supplement the cytologic diagnosis of malignancy in serous effusions. Current methods of analysis involve immediate preparation, but our study showed that prior culture of the cells is a more practical approach to the use of chromosome analysis in the routine cytology laboratory. This method permits the retrospective selection of specimens for chromosome analysis from patients in whom there is a strong clinical suspicion of malignant disease but who have negative or equivocal cytology reports. The preparative technique and the recognition of structural and numerical chromosome anomalies can be readily learned by the cytotechnologist and incorporated into the routine cytology laboratory.
细胞遗传学分析用于辅助浆液性积液恶性肿瘤的细胞学诊断。目前的分析方法包括立即制片，但我们的研究表明，对于常规细胞学实验室的染色体分析而言，细胞预先培养是一种更实用的方法。这种方法允许从临床上高度怀疑患有恶性疾病但细胞学报告为阴性或不明确的患者中回顾性选择用于染色体分析的标本。细胞技术人员可以很容易地学会制片技术以及识别染色体结构和数量异常，并将其纳入常规细胞学实验室的工作中。
