Strakhovskaia M G, Serdalina A M, Fraĭkin G Ia
Nauchnye Doki Vyss Shkoly Biol Nauki. 1983(3):25-8.
The photoreactivation of yeast (Saccharomyces cerevisiae) cells irradiated by far-UV-light has been studied. It has been shown that the near-UV-induced (334, 365 nm) synthesis of serotonin in yeast is an underlying cause of its photoreactivation action spectrum change. The effect of serotonin is due to its binding to far-UV-irradiated DNA (pyrimidine dimers) making them unavailable to the photoreactivating enzyme. The data obtained support the idea that serotonin affects the repair enzymes which are engaged in an elimination of lethal photoproducts from DNA.
对经远紫外线照射的酵母(酿酒酵母)细胞的光复活作用进行了研究。结果表明,酵母中近紫外线诱导(334、365纳米)的血清素合成是其光复活作用光谱变化的根本原因。血清素的作用是由于它与经远紫外线照射的DNA(嘧啶二聚体)结合,使它们无法被光复活酶作用。所获得的数据支持了血清素影响参与从DNA中消除致死性光产物的修复酶这一观点。