Radin R C, Greenberger P A, Patterson R, Ghory A
Clin Allergy. 1983 May;13(3):271-5. doi: 10.1111/j.1365-2222.1983.tb02598.x.
The purpose of this study was to determine whether exacerbations of allergic bronchopulmonary aspergillosis (ABPA) were associated with the total outdoor mould counts in the Chicago area. From 1976-1980, forty-nine flares of ABPA (new pulmonary infiltrate with elevation in total serum IgE) occurred in nineteen patients. Thirty-eight (77.5%) of flares occurred during months June through November in association with increased outdoor mould counts in Chicago. This association confirms earlier observations from the U.K. where during the peak mould season which occurs in winter months, there was an increased number of pulmonary infiltrates and average prednisone doses required in ABPA.
本研究的目的是确定变应性支气管肺曲霉病（ABPA）的病情加重是否与芝加哥地区的室外霉菌总数有关。1976年至1980年期间，19名患者出现了49次ABPA病情发作（新发肺部浸润伴血清总IgE升高）。其中38次（77.5%）发作发生在6月至11月，与芝加哥室外霉菌数量增加有关。这一关联证实了英国早期的观察结果，即在冬季的霉菌高峰期，ABPA患者的肺部浸润数量和所需的泼尼松平均剂量均有所增加。
