Kolman A, Näslund M
Mol Gen Genet. 1983;189(2):222-5. doi: 10.1007/BF00337808.
The interaction of UV-irradiation and ethylene oxide (EtO) on forward mutation frequencies in the lacI gene of E. coli strains 3835 and 3951 and on the frequency of leu+ revertants in E. coli WU36-10-89 were studied. Pre-exposure to low doses of UV-light with the following treatment by low and intermediate doses of EtO showed lack of additive effect in the mutagenic response in all strains studied. The number of mutants actually obtained in the respective experiments was much lower than the additive model predicted.
研究了紫外线照射与环氧乙烷（EtO）对大肠杆菌3835和3951菌株lacI基因正向突变频率以及大肠杆菌WU36 - 10 - 89中亮氨酸营养缺陷型回复突变体频率的相互作用。先用低剂量紫外线预处理，随后用低剂量和中等剂量的EtO处理，结果表明在所研究的所有菌株中，诱变反应均未表现出加性效应。在各自实验中实际获得的突变体数量远低于加性模型预测的数量。
