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与妊娠相关的复发性短暂性甲状腺功能亢进和甲状腺功能减退

Recurrent transient hyperthyroidism and hypothyroidism associated with pregnancy.

作者信息

Gossain V V, Rovner D R, Rhodes C E

出版信息

South Med J. 1983 Jun;76(6):808-10. doi: 10.1097/00007611-198306000-00033.

DOI:10.1097/00007611-198306000-00033
PMID:6344229
Abstract

We describe a female patient with insulin-dependent diabetes mellitus and autoimmune thyroiditis. Transient hyperthyroidism developed in the postpartum period in two successive pregnancies, followed by temporary hypothyroidism with eventual full recovery. The clinical course was consistent with "silent thyroiditis" and the circumstantial evidence suggested that alterations in the antibody titers due to pregnancy may have been responsible for these episodes. This case study serves to emphasize that hyperthyroidism and hypothyroidism in the postpartum period may be transient, and this fact should be considered in therapeutic management of such a patient.

摘要

我们描述了一位患有胰岛素依赖型糖尿病和自身免疫性甲状腺炎的女性患者。在连续两次怀孕期间的产后阶段出现了短暂性甲状腺功能亢进,随后是暂时性甲状腺功能减退,最终完全恢复。临床过程符合“寂静性甲状腺炎”,间接证据表明,妊娠导致的抗体滴度变化可能是这些发作的原因。本病例研究旨在强调产后甲状腺功能亢进和减退可能是短暂性的,在对此类患者进行治疗管理时应考虑这一事实。

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