Puig-Antich J, Weston B
Annu Rev Med. 1983;34:231-45. doi: 10.1146/annurev.me.34.020183.001311.
The authors review the evidence supporting the hypothesis of similarity or identity of prepubertal and adult major depressive disorders and give a state-of-the-art account of current assessment techniques, diagnosis, and treatment methods of prepubertal major depression. This is an area of child psychiatry where recent psychobiological research advances are fueling profound changes in traditional nosology and therapeutics. In addition, further understanding of early onset major depression is likely to throw considerable light on the nature and pathophysiology of depressive illness across ages.
作者回顾了支持青春期前和成人重度抑郁症相似或相同这一假说的证据，并对当前青春期前重度抑郁症的评估技术、诊断和治疗方法进行了最新阐述。这是儿童精神病学领域，近期心理生物学研究进展正在推动传统疾病分类学和治疗学发生深刻变革。此外，对早发性重度抑郁症的进一步理解可能会为不同年龄段抑郁症的本质和病理生理学提供相当多的启示。
