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Halothane hepatotoxicity: relation between metabolic activation, hypoxia, covalent binding, lipid peroxidation and liver cell damage.

作者信息

de Groot H, Noll T

出版信息

Hepatology. 1983 Jul-Aug;3(4):601-6. doi: 10.1002/hep.1840030421.

DOI:10.1002/hep.1840030421
PMID:6345332
Abstract
摘要

相似文献

1
Halothane hepatotoxicity: relation between metabolic activation, hypoxia, covalent binding, lipid peroxidation and liver cell damage.氟烷肝毒性：代谢活化、缺氧、共价结合、脂质过氧化与肝细胞损伤之间的关系。
Hepatology. 1983 Jul-Aug;3(4):601-6. doi: 10.1002/hep.1840030421.
2
An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia.氟烷肝毒性的动物模型：酶诱导和缺氧的作用。
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Enhanced in vivo-lipid peroxidation associated with halothane hepatotoxicity in rats.大鼠中与氟烷肝毒性相关的体内脂质过氧化增强。
Pharmacol Toxicol. 1988 Jul;63(1):52-6. doi: 10.1111/j.1600-0773.1988.tb00909.x.
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[A system of liver microsomal oxidation in hypoxia and hyperoxia].[缺氧和高氧状态下的肝脏微粒体氧化系统]
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The metabolism of halothane by hepatocytes: a comparison between free radical spin trapping and lipid peroxidation in relation to cell damage.肝细胞对氟烷的代谢：自由基自旋捕获与脂质过氧化作用在细胞损伤方面的比较
Chem Biol Interact. 1983 Sep 15;46(3):353-68. doi: 10.1016/0009-2797(83)90019-4.
6
Role of reactive intermediates in halothane associated liver injury.活性中间体在氟烷相关性肝损伤中的作用。
Adv Exp Med Biol. 1981;136 Pt A:603-18. doi: 10.1007/978-1-4757-0674-1_44.
7
Halothane-induced liver injury as a consequence of enhanced microsomal lipid peroxidation in guinea pigs.
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Halothane-dependent lipid peroxidation in human liver microsomes is catalyzed by cytochrome P4502A6 (CYP2A6).人肝微粒体中氟烷依赖性脂质过氧化由细胞色素P4502A6（CYP2A6）催化。
Anesthesiology. 2001 Aug;95(2):509-14. doi: 10.1097/00000542-200108000-00037.
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Investigation of the immunological basis of halothane-induced hepatotoxicity.氟烷诱导的肝毒性免疫基础的研究。
Adv Exp Med Biol. 1986;197:657-73. doi: 10.1007/978-1-4684-5134-4_61.
10
Hepatic necrosis caused by halothane and hypoxia in phenobarbital-treated rats.
Anesthesiology. 1979 Oct;51(4):327-33. doi: 10.1097/00000542-197910000-00009.

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Drug-Induced Liver Toxicity and Prevention by Herbal Antioxidants: An Overview.药物性肝毒性与草药抗氧化剂的预防：综述
Front Physiol. 2016 Jan 26;6:363. doi: 10.3389/fphys.2015.00363. eCollection 2015.
2
Halothane-induced hepatitis: A forgotten issue in developing countries: Halothane-induced hepatitis.氟烷性肝炎：发展中国家一个被遗忘的问题：氟烷性肝炎
Hepat Mon. 2011 Jan;11(1):3-6.
3
Antioxidants prevent depression of the acute hypoxic ventilatory response by subanaesthetic halothane in men.抗氧化剂可预防氟烷亚麻醉剂量对男性急性低氧通气反应的抑制作用。
J Physiol. 2002 Nov 1;544(3):931-8. doi: 10.1113/jphysiol.2002.025999.
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Halothane hepatotoxicity and hepatic free radical metabolism in guinea pigs; the effects of vitamin E.氟烷对豚鼠的肝毒性及肝脏自由基代谢；维生素E的影响
Can J Anaesth. 1996 Jul;43(7):741-8. doi: 10.1007/BF03017960.
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Halothane anaesthesia and liver damage.氟烷麻醉与肝损伤。
Br Med J (Clin Res Ed). 1984 Oct 27;289(6452):1136-9. doi: 10.1136/bmj.289.6452.1136.
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Biochemical studies on the metabolic activation of halogenated alkanes.卤代烷烃代谢活化的生化研究。
Environ Health Perspect. 1985 Dec;64:85-101. doi: 10.1289/ehp.856485.
7
Aetiology and pathophysiology of chronic liver disorders.慢性肝脏疾病的病因学与病理生理学
Drugs. 1990;40 Suppl 3:3-22. doi: 10.2165/00003495-199000403-00003.