Benvenuti C, Guidoni G, Longoni A, Mordini M
Int J Tissue React. 1983;5(1):61-5.
Forty patients affected by various rheumatic disorders (mainly osteoarthritis) were treated with flurbiprofen (300 mg daily) or diclofenac (200 mg daily) in a two-week, parallel group, randomized trial. Both drugs were clinically effective in all the parameters except for fingertip-to-floor distance and ESR. Flurbiprofen proved to be more effective than diclofenac in reducing pain on movement (p less than 0.01) and number of swollen joints (p less than 0.05). The doctor's overall assessment favoured flurbiprofen (p less than 0.10). The incidence and severity of side-effects were low and similar with the two drugs.
40名患有各种风湿性疾病（主要为骨关节炎）的患者，在一项为期两周的平行组随机试验中，接受氟比洛芬（每日300毫克）或双氯芬酸（每日200毫克）治疗。除指尖到地面距离和血沉外，两种药物在所有参数上均具有临床疗效。在减轻运动疼痛（p<0.01）和肿胀关节数量（p<0.05）方面，氟比洛芬被证明比双氯芬酸更有效。医生的总体评估更倾向于氟比洛芬（p<0.10）。两种药物的副作用发生率和严重程度均较低且相似。
