Viara M, Benvenuti C, Longoni A
Eur J Rheumatol Inflamm. 1983;6(2):192-6.
Thirty out-patients with rheumatoid arthritis aged from 3 yrs. (+/- 0.5 SEM) were included in a between-patient controlled trial comparing effectiveness and safety of flurbiprofen 300 mg daily and indomethacin 150 mg daily. The duration of the treatment was nine weeks. Both drugs allowed to reduce the initial dose of corticosteroids administered (-21% on flurbiprofen and -12% on indomethacin) and were effective in improving clinical signs of the disease such as number of swollen joints, grip strength, articular index and morning stiffness. Flurbiprofen was better tolerated (p less than 0.01).
30名年龄在3岁（±0.5标准误）的类风湿性关节炎门诊患者被纳入一项患者间对照试验，比较每日300毫克氟比洛芬和每日150毫克吲哚美辛的有效性和安全性。治疗持续时间为9周。两种药物均能降低所给予的皮质类固醇的初始剂量（氟比洛芬降低21%，吲哚美辛降低12%），并有效改善疾病的临床体征，如关节肿胀数、握力、关节指数和晨僵。氟比洛芬的耐受性更好（p小于0.01）。
