[Role of a change in oxygen concentration in modifying in vitro reproductive cell death. 3. Modification of radiosensitivity by compounds reducing oxygen].
作者信息
Korystov Iu N
出版信息
Radiobiologiia. 1983 May-Jun;23(3):318-22.
PMID:6346382
Abstract
The data are discussed concerning the protection of cells in vitro by the oxygen reducing agents. The analysis has demonstrated that the protective effect of sulfites can only be related to hypoxia they create. Hypoxia also contributes considerably to the protective effect of thiols (maximum DMF approximately 3). However the protective effect of thiols cannot wholly be attributed to hypoxia. The oxygen--independent component of the protective effect of thiols (maximum DMF approximately 1.5) is conditioned by the metabolic changes increasing the enzymic repair of potential damages.
摘要
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