Vennes J A
Semin Liver Dis. 1983 May;3(2):162-71. doi: 10.1055/s-2008-1040682.
Management of choledocholithiasis requires several strategies to solve the various clinical problems encountered. A maximal effort during cholecystectomy at discovery of the duct stones in almost one of every six patients should, of course, be continued. Cystic duct cholangiography should routinely be used in deciding whether to explore the common duct. Postexploratory choledochoscopy has demonstrated discovery value and will hopefully be increasingly used. More training and sharing of technical details is indicated. When a retained stone is discovered on T tube cholangiogram, several options are available with no one clearly superior. Waiting for the T tube tract to mature and attempting extraction via flexible endoscopes or Burhenne technique is probably most cost effective if appropriate skills are available, especially for small calculi. Calculi greater than 8 mm in diameter with some probability of having high cholesterol content may be best managed with monooctanoin infusion. Parenthetically, monooctanoin dissolution may reduce morbidity of ERS, since large stones that would require large, more risky sphincterotomies can in some instances be reduced to passable size by monooctanoin infusion via an endoscopically placed nasobiliary tube. Endoscopic sphincterotomy for retained stones is ordinarily reserved for patients in whom nonoperative retrieval has failed or the T tube has fallen out. When common duct obstruction due to stones occurs prior to or remote from cholecystectomy, ERS is the preferred method of management when available, under conditions previously noted. With improved discovery methods and less morbid therapeutic options, consequences of choledocholithiasis will be less formidable.
胆总管结石的治疗需要多种策略来解决所遇到的各种临床问题。当然,在每六例患者中几乎就有一例在胆囊切除术中发现胆管结石时应尽最大努力继续处理。在决定是否探查胆总管时应常规使用胆囊管胆管造影。探查后胆管镜检查已显示出其发现价值,有望得到越来越广泛的应用。这需要更多的培训并分享技术细节。当在T管胆管造影中发现残留结石时,有几种选择,没有一种明显更具优势。如果具备适当的技术,等待T管窦道成熟并尝试通过柔性内窥镜或Burhenne技术取出结石可能是最具成本效益的方法,特别是对于小结石。直径大于8mm且可能含有高胆固醇成分的结石可能最好通过单辛脂灌注来处理。顺便提一下,单辛脂溶解可能会降低内镜逆行性胆胰管造影术(ERS)的发病率,因为在某些情况下,需要进行大的、风险更高的括约肌切开术的大结石可以通过经内镜放置的鼻胆管进行单辛脂灌注缩小至可通过的大小。内镜括约肌切开术治疗残留结石通常仅适用于非手术取石失败或T管已脱落的患者。当在胆囊切除术之前或远离胆囊切除术时因结石导致胆总管梗阻时,在前面提到的条件下,ERS是可用时的首选治疗方法。随着发现方法的改进和治疗选择的低创伤性,胆总管结石的后果将不再那么可怕。