Byrd J P
South Med J. 1983 Jul;76(7):890-3. doi: 10.1097/00007611-198307000-00019.
Malignant hyperthermia, a rapidly progressive, frequently lethal syndrome was not described until quite recently. Although treatment with the drug dantrolene has changed its face, a clear understanding and deep respect for the syndrome are necessary to keep fatalities and tragic sequelae to a minimum. The etiology and pathophysiology, preanesthetic diagnosis, incidence, management of the acute crisis, and anesthesia for susceptible patients are discussed, and a successfully treated fulminant case is analyzed.
恶性高热是一种进展迅速、常危及生命的综合征，直到最近才被描述。尽管使用丹曲林治疗已经改变了其预后，但要将死亡率和悲惨后遗症降至最低，仍需要对该综合征有清晰的认识和高度重视。本文讨论了其病因和病理生理学、麻醉前诊断、发病率、急性危象的处理以及易感患者的麻醉，并分析了一例成功治疗的暴发性病例。
