Nakao T, Sugihashi A, Saga N, Tsunoda N, Kawata K
Am J Vet Res. 1983 May;44(5):888-90.
In 160 cows with ovarian cysts as determined by rectal palpation, differentiation was made of follicular cyst, luteal cyst, and cystic corpus luteum on the basis of milk progesterone concentrations estimated by an enzyme immunoassay before and at 10 days after cows were treated with gonadotropin-releasing hormone. Cows having a progesterone concentration in skim milk less than 1.0 ng/ml were considered to have follicular cysts and those with concentrations of 1.0 ng/ml or higher were regarded as the cases of luteal cyst or cystic corpus luteum. Luteal cyst was characterized by progesterone values remaining high in the cows for 10 days after treatment, and cystic corpus luteum was characterized by a decrease in progesterone concentration after cows were treated. By the rectal palpation procedure it was impossible to differentiate luteal cyst and cystic corpus luteum from follicular cyst. The frequencies of follicular cyst, luteal cyst, and cystic corpus luteum were 65%, 19%, and 16%, respectively. Of 104 cows with follicular cysts as defined by milk progesterone assay result, 73 (70%) responded to the treatment with gonadotropin-releasing hormone, the milk progesterone concentration increasing from 0.7 +/- 0.2 ng/ml (mean +/- SD) to 1.8 +/- 1.1 ng/ml. The accuracy of rectal palpation 10 days after treatment for judgment of luteinization of follicular cyst confirmed by milk progesterone analysis was only 30% (48 cows of 160).
对经直肠触诊确定患有卵巢囊肿的160头奶牛，根据用促性腺激素释放激素治疗前及治疗后10天通过酶免疫测定法估算的牛奶孕酮浓度，区分卵泡囊肿、黄体囊肿和黄体囊肿样结构。脱脂牛奶中孕酮浓度低于1.0 ng/ml的奶牛被认为患有卵泡囊肿，而浓度为1.0 ng/ml或更高的奶牛则被视为黄体囊肿或黄体囊肿样结构病例。黄体囊肿的特征是治疗后10天奶牛的孕酮值持续较高，而黄体囊肿样结构的特征是奶牛治疗后孕酮浓度下降。通过直肠触诊程序无法将黄体囊肿和黄体囊肿样结构与卵泡囊肿区分开来。卵泡囊肿、黄体囊肿和黄体囊肿样结构的发生率分别为65%、19%和16%。在根据牛奶孕酮检测结果定义为卵泡囊肿的104头奶牛中，73头（70%）对促性腺激素释放激素治疗有反应，牛奶孕酮浓度从0.7±0.2 ng/ml（平均值±标准差）增加到1.8±1.1 ng/ml。治疗后10天通过直肠触诊判断卵泡囊肿黄体化的准确性，经牛奶孕酮分析证实仅为30%（160头中的48头）。
