Douthwaite R, Dobson H
Cooper, Jinman and Partners, Hereford.
Vet Rec. 2000 Sep 23;147(13):355-9. doi: 10.1136/vr.147.13.355.
The aims of this study were to assess the accuracy of different common methods of differentiating between follicular and luteal ovarian cysts, and to monitor the response of the cysts to 12 days treatment with a progesterone-releasing intravaginal device (PRID). On the basis of agreement between the different methods, 25 of the 46 cases examined were diagnosed as follicular and 14 as luteal cysts; for the other seven cases the methods disagreed. The use of ultrasound was more accurate in diagnosing follicular cysts than luteal cysts, and combined with plasma progesterone concentrations gave the most accurate assessment of cyst type (92 per cent for follicular cysts and 82 per cent for luteal cysts). The mean (se) plasma progesterone concentration was lower in the cows with follicular cysts than in those with luteal cysts (0.29 [0.05] v 3.90 [0.63] ng/ml; P<0.05). Luteal cysts had thicker walls (5.3 [0.04] v 2.5 [0.2] mm; P<0.0001), and the wall thickness of all the cysts was positively correlated with plasma progesterone concentration (r=0.52, P<0.0004). Cows with luteal cysts had more additional follicles greater than 5 mm in diameter (P<0.01). In cows with follicular cysts and other follicles greater than 5 mm in diameter, the mean oestradiol concentration was 7.9 (1.8) pg/ml compared with 24.2 (3.1) pg/ml (P=0.002) in cows without other follicles greater than 5 mm in diameter on either ovary. At the time of PRID removal, plasma progesterone concentration had increased in the cows with follicular cysts to 1.59 (0.06) ng/ml (P<0.05) and decreased in the cows with luteal cysts to 0.87 (0.01) ng/ml (P<0.05), although there was no change in original cyst structure in 45 per cent of the cases. However, new ovarian structures were frequently observed during the treatment. The overall pregnancy rate for cows with both types of cyst after treatment was 50 per cent after three inseminations, but the first service pregnancy rate was only 18 per cent for cows with follicular cysts and 28 per cent for cows with luteal cysts. After treatment, the fertility of cows with follicular cysts was similar to that of paired herdmates, whereas cows with luteal cysts took 40 days longer to calve again than healthy herdmates. However, the culling rate was higher for cows with follicular cysts (41 v 11 per cent).
本研究的目的是评估区分卵泡性和黄体性卵巢囊肿的不同常用方法的准确性，并监测囊肿对使用释放孕酮的阴道装置（PRID）进行12天治疗的反应。根据不同方法之间的一致性，46例受检病例中有25例被诊断为卵泡囊肿，14例为黄体囊肿；另外7例的诊断方法存在分歧。超声在诊断卵泡囊肿方面比黄体囊肿更准确，结合血浆孕酮浓度对囊肿类型的评估最为准确（卵泡囊肿为92%，黄体囊肿为82%）。卵泡囊肿母牛的平均（标准误）血浆孕酮浓度低于黄体囊肿母牛（0.29[0.05]对3.90[0.63]纳克/毫升；P<0.05）。黄体囊肿的壁更厚（5.3[0.04]对2.5[0.2]毫米；P<0.0001），所有囊肿的壁厚与血浆孕酮浓度呈正相关（r=0.52，P<0.0004）。黄体囊肿母牛直径大于5毫米的额外卵泡更多（P<0.01）。在有卵泡囊肿且其他卵泡直径大于5毫米的母牛中，平均雌二醇浓度为7.9（1.8）皮克/毫升，而在两侧卵巢均无其他卵泡直径大于5毫米的母牛中为24.2（3.1）皮克/毫升（P=0.002）。在取出PRID时，卵泡囊肿母牛的血浆孕酮浓度升高至1.59（0.06）纳克/毫升（P<0.05），黄体囊肿母牛的血浆孕酮浓度降至0.87（0.01）纳克/毫升（P<0.05），尽管45%的病例中原始囊肿结构没有变化。然而，治疗期间经常观察到新的卵巢结构。两种囊肿类型的母牛治疗后经三次输精后的总体妊娠率为50%，但卵泡囊肿母牛的首次输精妊娠率仅为18%，黄体囊肿母牛为该28%。治疗后，卵泡囊肿母牛的繁殖力与配对的同群母牛相似，而黄体囊肿母牛再次产犊的时间比健康同群母牛长40天。然而，卵泡囊肿母牛的淘汰率更高（41%对11%）。
