Barela T D, Johnson J D, Hayek A
Clin Endocrinol Metab. 1983 Jul;12(2):429-46. doi: 10.1016/s0300-595x(83)80050-4.
In this chapter we have described the metabolic diseases which are known to have caused acidosis during the newborn period. We have also provided some diagnostic and treatment guidelines. The occurrence of acidosis in a newborn baby should initiate several actions, aimed simultaneously at treatment and diagnosis. An initial blood gas determination, accompanied by the results of serum electrolytes and glucose, will, in most instances, separate respiratory from metabolic causes. Finding of an increased anion gap and/or presence of hypoglycaemia should direct attention towards errors in intermediary metabolism.
在本章中,我们描述了已知在新生儿期会导致酸中毒的代谢性疾病。我们还提供了一些诊断和治疗指南。新生儿发生酸中毒时应采取多项措施,同时针对治疗和诊断。在大多数情况下,首次进行血气测定并结合血清电解质和血糖结果,将区分呼吸性病因和代谢性病因。发现阴离子间隙增加和/或存在低血糖应将注意力引向中间代谢的差错。