Zick R, Hürter P, Berger M, Lange P, Mitzkat H J
Dtsch Med Wochenschr. 1983 Aug 5;108(31-32):1178-82. doi: 10.1055/s-2008-1069718.
Diabetes-specific hand alterations (cheirarthropathy) were observed in 44 out of a total of 215 children and adolescents with insulin-dependent diabetes. In 28 of them limitations of movement in the proximal or (and) distal interphalangeal joints of one finger, and in the remaining 16 patients changes of at least two fingers were seen. Hand and shoulder joints or the vertebral column were not affected. In a control group of 110 probands without metabolic disorder only five showed cheirarthropathy. The frequency of diabetes-specific alterations of the hand increased with the age of the patients, the duration of diabetes and insulin requirements. In particular, the quality of metabolic control is of paramount importance for the as yet unclear pathogenesis of cheirarthropathy.
在总共215名胰岛素依赖型糖尿病儿童和青少年中，有44人出现了糖尿病特异性手部改变（手部关节病）。其中28人一个手指的近端或（和）远端指间关节活动受限，其余16名患者至少两个手指出现改变。手部和肩关节或脊柱未受影响。在110名无代谢紊乱的对照组先证者中，只有5人出现手部关节病。糖尿病特异性手部改变的发生率随患者年龄、糖尿病病程和胰岛素需求量增加。特别是，代谢控制质量对于手部关节病尚不清楚的发病机制至关重要。
