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[儿童及青少年糖尿病性手部病变发病率及程度的临床与实验室化学研究]

[Clinical and laboratory chemical studies of the incidence and extent of diabetic cheiropathy in childhood and adolescence].

作者信息

Scherbaum W A, Koubik J, Winkler G, Pfeiffer E F

出版信息

Med Klin (Munich). 1989 Jan 15;84(1):1-4.

PMID:2918849
Abstract

Diabetic cheiropathy is often not diagnosed because of a paucity of symptoms. In the present study, 100 type I diabetic patients and 20 controls were investigated. The age of patients ranged from seven to 26 years, the duration of diabetes was one to 23 years. Extension of hands by "prayer position", a hand-print and angle determinations of joints were considered for the determination of diabetic cheiropathy. The presence of cheiropathy was unrelated to the duration of diabetes. However, it was well correlated with the quality of blood sugar control and it was often associated with diabetic retinopathy: Diabetic cheiropathy was detected in 53 (53%) of the diabetic patients, and in 26 (49%) of them diabetic retinopathy was also diagnosed. Only three patients had a retinopathy without cheiropathy. On the basis of our results, diabetic cheiropathy is a surprisingly common feature in young type I-diabetics. It is not to be considered as a late complication but rather a sequel of badly controlled diabetes mellitus.

摘要

糖尿病性手部病变常因症状缺乏而未被诊断出来。在本研究中,对100例I型糖尿病患者和20名对照者进行了调查。患者年龄在7岁至26岁之间,糖尿病病程为1年至23年。通过“祈祷姿势”伸展双手、手印以及关节角度测定来确定糖尿病性手部病变。手部病变的存在与糖尿病病程无关。然而,它与血糖控制质量密切相关,且常与糖尿病视网膜病变相关:在53例(53%)糖尿病患者中检测到糖尿病性手部病变,其中26例(49%)还被诊断出患有糖尿病视网膜病变。只有3例患者有视网膜病变但无手部病变。根据我们的研究结果,糖尿病性手部病变在年轻的I型糖尿病患者中是一个惊人的常见特征。它不应被视为晚期并发症,而应被视为糖尿病控制不佳的后果。

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