Amirov N Sh, Antonov D V
Fiziol Zh SSSR Im I M Sechenova. 1983 May;69(5):685-8.
12 proteolytic fractions were obtained with disc--electrophoresis from the gastric mucosa in healthy dogs. 5 proteases (I group) were only found in fundus and gastric body whereas 7 those (II group) were found in antrum as well. Study of the fractions proteolytic activity revealed two of them to be active in pH 1.0-5.0; two in pH 4.0-5.0; one in pH 1.0-2.0; the area of other proteases activity involved 3-4 units of pH. The considerable amount of proteases and the large area of their activity seem to secure the protein hydrolysis in the stomach in different pH values of eaten food.
通过圆盘电泳从健康犬的胃黏膜中获得了12种蛋白水解组分。5种蛋白酶(I组)仅在胃底和胃体中发现,而另外7种(II组)在胃窦中也有发现。对这些组分的蛋白水解活性研究表明,其中两种在pH 1.0 - 5.0有活性;两种在pH 4.0 - 5.0有活性;一种在pH 1.0 - 2.0有活性;其他蛋白酶的活性范围涉及3 - 4个pH单位。大量的蛋白酶及其较大的活性范围似乎确保了在食用食物的不同pH值条件下胃内蛋白质的水解。