Amirov N Sh, Antonov D V, Trubitsyna I E
Biull Eksp Biol Med. 1977 Apr;83(4):408-11.
Disc-electrophoretic investigation of proteases of the gastric juice of dogs under normal conditions and in experimental atophan ulcer of the stomach demonstrated that in fasting dogs ulceration was accompanied by marked quantitative changes in the protease spectrum. Fraction No. 6 showed a significant elevation against the background of total reduction of proteolytic fraction of the gastric juice in sham feeding of ulcerated dogs. Sham feeding replete ulcerated dogs indicated a marked increase of fractions No.1 and No.2. The noted changes of the gastric juice protease spectrum may be of ulcerogenic significance.
对正常条件下及实验性胃阿托方溃疡犬胃液蛋白酶进行圆盘电泳研究表明，在禁食犬中，溃疡形成伴随着蛋白酶谱的显著定量变化。在溃疡犬假饲时，胃液蛋白水解部分总量减少的背景下，第6组分显著升高。给饱食的溃疡犬假饲表明第1和第2组分显著增加。所观察到的胃液蛋白酶谱变化可能具有致溃疡意义。
