Spicak V
J Int Med Res. 1983;11(3):173-8. doi: 10.1177/030006058301100308.
Report on a double-blind parallel group comparison of ketotifen and placebo in two groups of twenty-five children with extrinsic bronchial asthma. Duration of treatment: 12 weeks, dosage adapted to body-weight, 0.5-1 mg b.i.d. Main parameters: Overall assessment of efficacy by the treating physician, total duration and frequency of asthmatic episodes per observation period. In all parameters ketotifen was far superior to placebo in spite of decreased concomitant bronchodilator therapy. The tolerance and acceptability of the compound was good.
关于在两组各25名外源性支气管哮喘儿童中进行的酮替芬与安慰剂双盲平行组比较的报告。治疗持续时间：12周，剂量根据体重调整，每日两次，每次0.5 - 1毫克。主要参数：治疗医生对疗效的总体评估、每个观察期哮喘发作的总持续时间和频率。尽管联合使用的支气管扩张剂治疗有所减少，但在所有参数方面，酮替芬均远优于安慰剂。该化合物的耐受性和可接受性良好。
